mreps: Efficient and flexible detection of tandem repeats in DNA

Roman Kolpakov, Ghizlane Bana, Gregory Kucherov

Результат исследований: Вклад в журналСтатьярецензирование

303 Цитирования (Scopus)

Аннотация

The presence of repeated sequences is a fundamental feature of genomes. Tandemly repeated DNA appears in both eukaryotic and prokaryotic genomes, it is associated with various regulatory mechanisms and plays an important role in genomic fingerprinting. In this paper, we describe mreps, a powerful software tool for a fast identification of tandemly repeated structures in DNA sequences. mreps is able to identify all types of tandem repeats within a single run on a whole genomic sequence. It has a resolution parameter that allows the program to identify 'fuzzy' repeats. We introduce main algorithmic solutions behind mreps, describe its usage, give some execution time benchmarks and present several case studies to illustrate its capabilities. The mreps web interface is accessible through http://www.loria.fr/mreps/.

Язык оригиналаАнглийский
Страницы (с-по)3672-3678
Число страниц7
ЖурналNucleic Acids Research
Том31
Номер выпуска13
DOI
СостояниеОпубликовано - 1 июл. 2003
Опубликовано для внешнего пользованияДа

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Подробные сведения о темах исследования «mreps: Efficient and flexible detection of tandem repeats in DNA». Вместе они формируют уникальный семантический отпечаток (fingerprint).

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