Ultrasonically assisted fabrication of vaterite submicron-sized carriers

Yu I. Svenskaya, H. Fattah, A. M. Zakharevich, D. A. Gorin, G. B. Sukhorukov, B. V. Parakhonskiy

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)


Ultrasonically accomplished precipitation of calcium carbonate was demonstrated as a novel beneficial method for the formation of porous submicron vaterite particles with low dispersity, high mass yield, and the "scaling up" possibility. The effect of sonication on the size and crystallographic phase of formed particles was investigated by comparing this method with a magnetic stirring and non-stirring interfusion. By virtue of their porosity, vaterite particles allow the different substance incorporation. The loading properties of synthesized particles were demonstrated for high molecular weight substance (labeled protein), as well as for low molecular one (fluorescent dye). Such features open up perspectives of drug encapsulation and delivery for the vaterite submicron carriers.

Original languageEnglish
Pages (from-to)618-624
Number of pages7
JournalAdvanced Powder Technology
Issue number2
Publication statusPublished - 1 Mar 2016
Externally publishedYes


  • Calcium carbonate
  • Microparticles
  • Porous particles
  • Submicron particles
  • Ultrasound
  • Vaterite


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