Tree reconciliation: Reconstruction of species phylogeny by phylogenetic gene trees

V. V. V'yugin, M. S. Gelfand, V. A. Lyubetsky

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


It is well known that phylogenetic trees derived from different protein families are often incongruent. This is explained by mapping errors and by the essential processes of gene duplication, loss, and horizontal transfer. Therefore, the problem is to derive a "consensus" tree best fitting the given set of gene trees. This work presents a new method of deriving this tree. The method is different from the existing ones, since it considers not only the topology of the initial gene trees, but also the reliability of their branches. Thereby one can explicitly take into account the possible errors in the gene trees caused by the absence of reliable models of sequence evolution, by uneven evolution of different gene families and taxonomic groups, etc.

Original languageEnglish
Pages (from-to)650-658
Number of pages9
JournalMolecular Biology
Issue number5
Publication statusPublished - 2002
Externally publishedYes


  • Eukaryotes
  • Mitochondrial genomes
  • Phylogenetic protein tree
  • Phylogenetic species tree
  • Tree mapping
  • Tree reconciliation


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