Tissue perfusability assessment from capillary velocimetry data via the multicompartment Windkessel model

Elena S. Stiukhina, Maxim A. Kurochkin, Victor A. Klochkov, Ivan V. Fedosov, Dmitry E. Postnov

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Citations (Scopus)

Abstract

A method is presented to obtain information on tissue perfusability from capillary velocimetry experiments coupled with venous occlusion probe. The method based on data fitting to developed mathematical model describing the blood flow redistribution caused by the introduced occlusion. Using mathematical modeling, we identify the segment of velocity time courses that corresponds to tissue swelling process and thus allows ones quantify it. We also compared the results of direct measurement of red blood cells (RBCs) velocity with time courses obtained from finger-placed sensors of two types: (i) photoplethysmographic sensor used in pulsometry and (ii) piezoelectric sensor for sphygmography. The obtained results suggest the measurable contribution of RBCs aggregation process in optical pulse signal formation.

Original languageEnglish
Title of host publicationSaratov Fall Meeting 2014
Subtitle of host publicationOptical Technologies in Biophysics and Medicine XVI; Laser Physics and Photonics XVI; and Computational Biophysics
EditorsDmitry E. Postnov, Elina A. Genina, Kirill V. Larin, Vladimir L. Derbov, Valery V. Tuchin
PublisherSPIE
ISBN (Electronic)9781628415643
DOIs
Publication statusPublished - 2014
Externally publishedYes
EventSaratov Fall Meeting 2014: Optical Technologies in Biophysics and Medicine XVI; Laser Physics and Photonics XVI; and Computational Biophysics, SFM 2014 - Saratov, Russian Federation
Duration: 23 Sep 201426 Sep 2014

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9448
ISSN (Print)1605-7422

Conference

ConferenceSaratov Fall Meeting 2014: Optical Technologies in Biophysics and Medicine XVI; Laser Physics and Photonics XVI; and Computational Biophysics, SFM 2014
Country/TerritoryRussian Federation
CitySaratov
Period23/09/1426/09/14

Keywords

  • blood ow velocity
  • microcirculation
  • particle image velocimetry
  • photoplethys-mography
  • Windkessel model

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