Supermolecule-assisted imaging of low-molecular-weight quaternary-ammonium compounds by MALDI-MS of their non-covalent complexes with cucurbit[7]uril

Di Chen, Jun Han, Juncong Yang, David Schibli, Zhenzhong Zhang, Christoph H. Borchers

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Cucurbit[7]uril was used to form non-covalent complexes with low-molecular-weight quaternary-ammonium compounds for their indirect analysis by MALDI-MS. By shifting the ion signals to a higher and interference-free mass region, the distributions of neurine, choline, and phosphocholine in rat brain were visualized by MALDI imaging with high selectivity and good sensitivity.

Original languageEnglish
Pages (from-to)34261-34265
Number of pages5
JournalRSC Advances
Volume10
Issue number56
DOIs
Publication statusPublished - 15 Sep 2020

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