RNA polymerase structure-function: Insights into points of transcriptional regulation

Konstantin Severinov

Research output: Contribution to journalReview articlepeer-review

46 Citations (Scopus)

Abstract

The crystal structure of Thermus aquaticus RNA polymerase (RNAP) with 3.3 Å resolution has recently been described. The high degree of sequence similarity between T. aquaticus RNAP and the prototypical RNAP from Escherichia coli invites comparison of the new structural data with genetic and biochemical results that defined the interaction sites of E. coli RNAP with transcription regulators.

Original languageEnglish
Pages (from-to)118-125
Number of pages8
JournalCurrent Opinion in Microbiology
Volume3
Issue number2
DOIs
Publication statusPublished - 1 Apr 2000
Externally publishedYes

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