Release mechanisms for polyelectrolyte capsules

Bruno G. De Geest, Niek N. Sanders, Gleb B. Sukhorukov, Joseph Demeester, Stefaan C. De Smedt

Research output: Contribution to journalArticlepeer-review

451 Citations (Scopus)

Abstract

Polyelectrolyte capsules have recently been introduced as new microscopic vehicles which could have high potential in the biomedical field. In this critical review we give an introduction to the layer-by-layer (LbL) technique which is used to fabricate these polyelectrolyte capsules as well as to the different triggers that have been exploited to obtain drug release from these capsules. Furthermore, other types of triggered delivery systems are compared and critically discussed with regard to their clinical relevance. (171 references.).

Original languageEnglish
Pages (from-to)636-649
Number of pages14
JournalChemical Society Reviews
Volume36
Issue number4
DOIs
Publication statusPublished - 27 Mar 2007
Externally publishedYes

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