Regulation of flagellar gene expression in Bacteria

I. A. Osterman, Yu Yu Dikhtyar, A. A. Bogdanov, O. A. Dontsova, P. V. Sergiev

Research output: Contribution to journalReview articlepeer-review

31 Citations (Scopus)


The flagellum of a bacterium is a supramolecular structure of extreme complexity comprising simultaneously both a unique system of protein transport and a molecular machine that enables the bacterial cell movement. The cascade of expression of genes encoding flagellar components is closely coordinated with the steps of molecular machine assembly, constituting an amazing regulatory system. Data on structure, assembly, and regulation of flagellar gene expression are summarized in this review. The regulatory mechanisms and correlation of the process of regulation of gene expression and flagellum assembly known from the literature are described.

Original languageEnglish
Pages (from-to)1447-1456
Number of pages10
JournalBiochemistry (Moscow)
Issue number11
Publication statusPublished - 1 Nov 2015
Externally publishedYes


  • bacteria
  • flagella
  • molecular machine
  • motility
  • transcriptional control


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