Photolysis triggered sealing of multilayer capsules to entrap small molecules

Qiangying Yi, Gleb B. Sukhorukov

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


Novel microcapsule systems containing UV-responsive diazonium groups were fabricated as microcontainers for cargo substance encapsulation by using a layer-by-layer (LbL) assembly technique. Upon direct exposure to UV light with a wavelength of approximately 380 nm, the diazonium groups of diazoresion (DAR) rapidly reacted with sulfonate or diazo-sulfonate groups of counterpart polyelectrolytes, which converted electrostatic interactions to covalent bonds, demonstrating an effective in situ cross-linking within multilayers via photolysis. Such chemical transition eliminated the paired ionic groups, therefore generating more hydrophobic multilayer shells, offering a unique approach to seal the porous polyelectrolyte capsule shells. Fluorescent molecule rhodamine B (RhB) was consequently studied as a typical example for small molecule encapsulation. Results indicated that the dye was remarkably retained within the microcapsules after UV-triggered capsule shell sealing.

Original languageEnglish
Pages (from-to)6723-6731
Number of pages9
JournalACS Applied Materials and Interfaces
Issue number14
Publication statusPublished - 24 Jul 2013
Externally publishedYes


  • capsule
  • diazonium
  • encapsulation
  • layer-by-layer
  • photolysis


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