Optimization of ionization conditions for analysis of humic substances from natural waters using Electrospray Ionization Fourier Transform Ion Cyclotron Resonance mass spectrometry (ESI FTICR MS)

E. V. Kunenkov, A. S. Kononikhin, I. V. Perminova, A. V. Garmash, I. A. Popov, E. N. Nikolaev

Research output: Contribution to journalArticlepeer-review

Abstract

An approach to optimizing conditions of acquiring Electrospray Ionization Fourier Transform Ion Cyclotron Resonance mass spectra (ESI FTICR MS) was suggested. This method was employed to study the influence of cone voltage and the composition of the solution on peak intensity in ESI FTICR mass spectra of natural water humic substances. A presence of water in methanol solution was shown to reduce signal intensity significantly. The highest integral intensity of peaks selected was reached on 110 mg/l sample solution in acetonitrile and cone voltage 3.0 kV. The number of peaks to which molecular formulas were assigned, including doubly-charged peaks, was increased using these conditions.

Original languageEnglish
Pages (from-to)300-303
Number of pages4
JournalMoscow University Chemistry Bulletin
Volume65
Issue number5
DOIs
Publication statusPublished - Oct 2010
Externally publishedYes

Keywords

  • electrospray ionization
  • Fourier transform ion cyclotron resonance mass spectrometry
  • humic substances
  • natural waters

Fingerprint

Dive into the research topics of 'Optimization of ionization conditions for analysis of humic substances from natural waters using Electrospray Ionization Fourier Transform Ion Cyclotron Resonance mass spectrometry (ESI FTICR MS)'. Together they form a unique fingerprint.

Cite this