Ocena wyników leczenia chirurgicznego chorych na mi̧saki przestrzeni zaotrzewnowej

Translated title of the contribution: The outcomes of surgical treatment of retroperitoneal soft tissue sarcoma

Paweł Piotrowski, Piotr Rutkowski, Wirginiusz Dziewirski, Zbigniew I. Nowecki, Marcin Zdzienicki, Andrzej Cichocki, Włodzimierz Ruka

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Background. The purpose of the study was to analyze the results of the surgical treatment of retroperitoneal soft tissue sarcomas (RSTS) and clinical-pathological factors influencing on treatment outcomes. Patients and methods. We analyzed 103 adult patients with RSTS treated in one institution between 04/1994 and 02/2000. There were 88 recurrent tumors (85.5%) and all tumors exceeded 5 cm. In 33 patients (32%) one or more adjacent organs were resected together with the tumor. Median follow-up time for survivors was 31 months. Results. Estimated 2-year and 5-year overall survival (OS) rateswere63% (±5%) and34% (±5%), respectively, and2- year and 5-year disease-free survival (DFS) rates were 45% (±5%) and 23% (±5%), respectively. In a multivariate analysis the only factor, which demonstrated positive impact on OS and DFS was low pathological grade of the tumor (hazard ratio for Gl tumors was 0.36 and 0.5, respectively). Patients after radical resection of the sarcoma with any adjacent organs had at least comparable survivals when compared to patients in whom resection had been limited to the tumor only. Conclusions. We have confirmed that the most important factor determining the outcomes of treatment of patients with retroperitoneal sarcoma (both in terms of overall and disease-free survival) is the histological grade of tumors. The radicality of surgery is also an important factor and it seems that a more radical resection of primary tumor with adjacent organs may increase the chances for cure.

Translated title of the contributionThe outcomes of surgical treatment of retroperitoneal soft tissue sarcoma
Original languagePolish
Pages (from-to)9-14
Number of pages6
JournalNowotwory
Volume59
Issue number1
Publication statusPublished - 2009
Externally publishedYes

Keywords

  • Prognosis
  • Retroperitoneal
  • Soft tissue sarcoma
  • Surgery

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