Modification of nucleic acids using [3+2] dipolar cycloaddition of azides and alkynes

A. V. Ustinov, I. A. Stepanova, V. V. Dubniakova, T. S. Zatsepin, E. V. Nozhevnikova, V. A. Korshun

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)

Abstract

The use of the reaction of azide and alkyne cycloaddition for the synthesis of nucleic acid conjugates and DNA oligomer analogues is considered. The data on chemical and enzymatic techniques of azides and alkynes introduction into DNA are summarized.

Original languageEnglish
Pages (from-to)437-481
Number of pages45
JournalBioorganicheskaia khimiia
Volume36
Issue number4
Publication statusPublished - Jul 2010
Externally publishedYes

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