Mitochondrial matrix processes

I. O. Mazunin, S. A. Levitskii, M. V. Patrushev, P. A. Kamenski

Research output: Contribution to journalReview articlepeer-review

8 Citations (Scopus)

Abstract

Mitochondria possess their own genome that, despite its small size, is critically important for their functioning, as it encodes several dozens of RNAs and proteins. All biochemical processes typical for bacterial and nuclear DNA are described in mitochondrial matrix: replication, repair, recombination, and transcription. Commonly, their mechanisms are similar to those found in bacteria, but they are characterized by several unique features. In this review, we provide an overall description of mitochondrial matrix processes paying special attention to the typical features of such mechanisms.

Original languageEnglish
Pages (from-to)1418-1428
Number of pages11
JournalBiochemistry (Moscow)
Volume80
Issue number11
DOIs
Publication statusPublished - 1 Nov 2015
Externally publishedYes

Keywords

  • mitochondria
  • mtDNA
  • nucleoid
  • recombination
  • repair
  • replication
  • transcription

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