Macromolecule Loading into Spherical, Elliptical, Star-Like and Cubic Calcium Carbonate Carriers

Bogdan V. Parakhonskiy, Alexey M. Yashchenok, Senem Donatan, Dmitry V. Volodkin, Francesco Tessarolo, Renzo Antolini, Helmuth Möhwald, Andre G. Skirtach

Research output: Contribution to journalArticlepeer-review

68 Citations (Scopus)

Abstract

We fabricated calcium carbonate particles with spherical, elliptical, star-like and cubical morphologies by varying relative salt concentrations and adding ethylene glycol as a solvent to slow down the rate of particle formation. The loading capacity of particles of different isotropic (spherical and cubical) and anisotropic (elliptical and star-like) geometries is investigated, and the surface area of such carriers is analysed. Potential applications of such drug delivery carriers are highlighted.

Original languageEnglish
Pages (from-to)2817-2822
Number of pages6
JournalChemPhysChem
Volume15
Issue number13
DOIs
Publication statusPublished - 15 Sep 2014
Externally publishedYes

Keywords

  • adsorption
  • calcium
  • drug delivery
  • nanoparticles
  • solid-state structures

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