Laser-assisted fabrication of tissue engineering scaffolds from titanium alloys

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Citation (Scopus)

Abstract

The chapter outlines recent studies in layer-by-layer synthesis of 3-D porous scaffolds, including the biocompatibility of the 3-D-matrix from nitinol (NiTi intermetallic phase) and nitinol with hydroxyapatite in comparison with titanium. The correlation between computer-aided modelling of 3-D scaffolds, optimal laser fabrication regimes, microstructure, and chemical and biological properties is discussed. Research has been carried out both for the forward and inverse directions during synthesis, that is, on the basis of dynamic proliferation and osteointegration results in 3-D scaffolds, in order to improve the design, microstructure, and material choice. Original ideas are proposed for the porous drug delivery system fabrication from shape memory nitinol.

Original languageEnglish
Title of host publicationLaser Surface Engineering
Subtitle of host publicationProcesses and Applications
PublisherElsevier Inc.
Pages603-651
Number of pages49
ISBN (Electronic)9781782420798
ISBN (Print)9781782420743
DOIs
Publication statusPublished - 2015
Externally publishedYes

Keywords

  • Drug delivery systems
  • Multipotent mesenchymal stem cells
  • Nitinol
  • Scaffolds
  • Selective laser sintering
  • Shape memory effect

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