Inline cartridge extraction for rapid brain tumor tissue identification by molecular profiling

Stanislav I. Pekov, Vasily A. Eliferov, Anatoly A. Sorokin, Vsevolod A. Shurkhay, Evgeny S. Zhvansky, Alexander S. Vorobyev, Alexander A. Potapov, Eugene N. Nikolaev, Igor A. Popov

    Research output: Contribution to journalArticlepeer-review

    12 Citations (Scopus)

    Abstract

    The development of perspective diagnostic techniques in medicine requires efficient high-throughput biological sample analysis methods. Here, we present an inline cartridge extraction that facilitates the screening rate of mass spectrometry shotgun lipidomic analysis of tissue samples. We illustrate the method by its application to tumor tissue identification in neurosurgery. In perspective, this high-performance method provides new possibilities for the investigation of cancer pathogenesis and metabolic disorders.

    Original languageEnglish
    Article number18960
    JournalScientific Reports
    Volume9
    Issue number1
    DOIs
    Publication statusPublished - 1 Dec 2019

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