Improved Electroactivity of Redox Probes onto Electropolymerized Azidomethyl-PEDOT: Enabling Click Chemistry for Advanced (Bio)Sensors

Vera A. Shavokshina, Maria A. Komkova, Ilya O. Aparin, Timofei S. Zatsepin, Arkady A. Karyakin, Egor A. Andreev

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We report on improved electroactivity of redox probes onto chloromethyl- and azidomethyl-substituted poly(3,4-ethylenedioxythiophene) in terms of up to a 2000-fold increased electron transfer rate. Modification of screen-printed carbon with the polymers provides a reversible electrochemical behavior of both cationic and anionic redox couples. The consequent increase in voltammetric response toward [Fe(CN)6]3-/4- couple in a neutral medium stipulates 200 times enhanced sensitivity to its structural analog Prussian blue-based nanozymes "artificial peroxidase". We believe, the combination of azide functionality enabling a versatile click chemistry with advanced electroactivity onto elaborated interfaces demonstrated in this paper is revolutionary for electrochemical (bio)sensing.

Original languageEnglish
Pages (from-to)1518-1524
Number of pages7
JournalACS Applied Polymer Materials
Volume3
Issue number3
DOIs
Publication statusPublished - 12 Mar 2021

Keywords

  • electrochemical (bio)sensor
  • heterogeneous electron transfer rate
  • poly(3,4-ethylenedioxythiophene)
  • Prussian blue nanoparticles
  • screen-printed carbon electrode

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