Hybrid nanophotonic-microfluidic sensor for highly sensitive liquid and gas analyses

Aleksei Kuzin, Vasiliy Chernyshev, Vadim Kovalyuk, Pavel An, Alexander Golikov, Roman Ozhegov, Dmitry Gorin, Nikolay Gippius, Gregory Goltsman

Research output: Contribution to journalArticlepeer-review

Abstract

Today, a lab-on-a-chip is one of the most promising ways to create sensor devices for gas and liquid analysis for environmental monitoring, early diagnosis, and treatment effectiveness assessment. On the one hand, this requires a large number of measurements and, on the other hand, involves minimum consumption of the test analytes. Combination of highly sensitive photonic integrated circuits (PICs) with microfluidic channels (MFCs) is necessary to solve this problem. In this work, PICs based on a silicon nitride platform integrated with MFCs for studying liquids and gases were developed. Different concentrations of isopropanol in de-ionized water were used as the analyte. Based on this, the sensitivity (S) and detection limit (DL) of the analyzed solution were evaluated. Entire system calibration was carried out to calculate S and DL, considering experimental and numerical simulation data. This development may be of interest as a promising platform for environmental monitoring and realization of point-of-care strategy for biomedical applications.

Original languageEnglish
Pages (from-to)2358-2361
Number of pages4
JournalOptics Letters
Volume47
Issue number9
DOIs
Publication statusPublished - 1 May 2022

Fingerprint

Dive into the research topics of 'Hybrid nanophotonic-microfluidic sensor for highly sensitive liquid and gas analyses'. Together they form a unique fingerprint.

Cite this