Highly localized laser-induced vascular responses

Elena S. Stiukhina, Maxim A. Kurochkin, Ivan V. Fedosov, Dmitry E. Postnov

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

The assessment of functioning microcirculatory network implies usage of adequate tools for testing the network responses on local changes of vessels state. While there are well-developed and widely used methods, such as focal application of vasoactive substances, or electric stimulation, there is a need for a non-destructive (and ideally-non-contact) and local method of impact a single vessel in order to trigger the network responce. In this paper, we investigate the possibility of applying the effect of a reversible change in the diameter of a blood vessel caused by laser radiation as a functional test of a microcirculatory system. For this purpose, we combine this effect with the method of micro-PIV (particle image velocimetry), which provides information on both the dynamics of blood flow in neighboring segments and the changes in their diameters.

Original languageEnglish
Title of host publicationSaratov Fall Meeting 2017
Subtitle of host publicationLaser Physics and Photonics XVIII; and Computational Biophysics and Analysis of Biomedical Data IV
EditorsDmitry E. Postnov, Vladimir L. Derbov
PublisherSPIE
ISBN (Electronic)9781510620032
DOIs
Publication statusPublished - 2018
Externally publishedYes
EventSaratov Fall Meeting 2017: Laser Physics and Photonics XVIII; and Computational Biophysics and Analysis of Biomedical Data IV - Saratov, Russian Federation
Duration: 26 Sep 201730 Sep 2017

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10717
ISSN (Print)1605-7422

Conference

ConferenceSaratov Fall Meeting 2017: Laser Physics and Photonics XVIII; and Computational Biophysics and Analysis of Biomedical Data IV
Country/TerritoryRussian Federation
CitySaratov
Period26/09/1730/09/17

Keywords

  • Chicken embryo
  • Laser-induced
  • Microcirculation
  • PIV
  • Vascular tone

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