Finely tuned Prussian blue-based nanoparticles and their application in disease treatment

Yong Gao, Guocan Yu, Kuoran Xing, Dmitry Gorin, Yuri Kotelevtsev, Weijun Tong, Zhengwei Mao

Research output: Contribution to journalReview articlepeer-review

9 Citations (Scopus)

Abstract

The Prussian blue (PB) based nanostructure is a mixed-valence coordination network with excellent biosafety, remarkable photothermal effect and multiple enzyme-mimicking behaviours. Compared with other nanomaterials, PB-based nanoparticles (NPs) exhibit several unparalleled advantages in biomedical applications. This review begins with the chemical composition and physicochemical properties of PB-based NPs. The tuning strategies of PB-based NPs and their biomedical properties are systemically demonstrated. Afterwards, the biomedical applications of PB-based NPs are comprehensively recounted, mainly focusing on treatment of tumors, bacterial infection and inflammatory diseases. Finally, the challenges and future prospects of PB-based NPs and their application in disease treatment are discussed.

Original languageEnglish
Pages (from-to)7121-7134
Number of pages14
JournalJournal of materials chemistry. B
Volume8
Issue number32
DOIs
Publication statusPublished - 19 Aug 2020

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