Evaluating the mitochondrial dna copy number in leukocytes and adipocytes from metabolic syndrome patients: pilot study

O. I. Mozheĭ, P. A. Zatolokin, M. A. Vasilenko, L. S. Litvinova, E. V. Kirienkova, I. O. Mazunin

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

The metabolic syndrome is a complex of metabolic, hormonal and clinical disorders. Defects in mitochondrial functions play an important role in the metabolic syndrome pathogenesis. Here, mitochondrial DNA (mtDNA) copy number variations were evaluated different fat tissue and peripheral blood leukocyte samples from metabolic syndrome patients ranked by, body mass indexes. It was elucidated a tendency in decreasing the mtDNA copy number with increasing a body mass index.

Original languageEnglish
Pages (from-to)677-681
Number of pages5
JournalMolekulyarnaya Biologiya
Volume48
Issue number4
Publication statusPublished - 1 Jul 2014
Externally publishedYes

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