Effect of dilution on aggregation of nanoparticles of polycarboxylic derivative of fullerene C60

A. G. Bobylev, N. V. Pen'kov, P. A. Troshin, S. V. Gudkov

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

In this work, we investigated the effect of dilution on aggregation of nanoparticles of the polycarboxylic derivative of fullerene C60. It is shown that the diminution of the concentration of PCDF-1 in aqueous medium leads to a decreased amount of aggregates of fullerene and an increased amount of single molecules. This can potentially interfere with the biological activity of a compound on one molecule basis. Addition of organic and inorganic salts to the aqueous medium with fullerene derivative leads to intense disaggregation of PCDF-1. The data obtained suggest an explanation of non-stoichiometric nature of neutralization of reactive oxygen species by derivatives of fullerenes, as well as provide new insight into the physical meaning of the work on the impact of nanoparticles at ultra-low concentrations on biological objects.

Original languageEnglish
Pages (from-to)38-43
Number of pages6
JournalBiofizika
Volume60
Issue number1
Publication statusPublished - 1 Jan 2015
Externally publishedYes

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