Consciousness in a multilevel architecture: Evidence from the right side of the brain

Boris M. Velichkovsky, Olga A. Krotkova, Artemy A. Kotov, Vyacheslav A. Orlov, Vitaly M. Verkhlyutov, Vadim L. Ushakov, Maxim G. Sharaev

    Research output: Contribution to journalArticlepeer-review

    24 Citations (Scopus)

    Abstract

    By taking into account Bruce Bridgeman's interest in an evolutionary framing of human cognition, we examine effective (cause-and-effect) connectivity among cortical structures related to different parts of the triune phylogenetic stratification: archicortex, paleocortex and neocortex. Using resting-state functional magnetic resonance imaging data from 25 healthy subjects and spectral Dynamic Causal Modeling, we report interactions among 10 symmetrical left and right brain areas. Our results testify to general rightward and top-down biases in excitatory interactions of these structures during resting state, when self-related contemplation prevails over more objectified conceptual thinking. The right hippocampus is the only structure that shows bottom-up excitatory influences extending to the frontopolar cortex. The right ventrolateral cortex also plays a prominent role as it interacts with the majority of nodes within and between evolutionary distinct brain subdivisions. These results suggest the existence of several levels of cognitive-affective organization in the human brain and their profound lateralization.

    Original languageEnglish
    Pages (from-to)227-239
    Number of pages13
    JournalConsciousness and Cognition
    Volume64
    DOIs
    Publication statusPublished - Sep 2018

    Keywords

    • Consciousness
    • Dynamic Causal Modeling (DCM)
    • Egocentric spatial representation
    • Frontopolar cortex
    • Hippocampal formation
    • Lateralization
    • Levels of cognitive organization
    • Resting state
    • Self-referential cognition
    • Ventrolateral prefrontal-amygdala emotional pathway

    Fingerprint

    Dive into the research topics of 'Consciousness in a multilevel architecture: Evidence from the right side of the brain'. Together they form a unique fingerprint.

    Cite this