Benchmarking of programs that predict the position of transmembrane segments in beta-barrel proteins

N. S. Sadovskaya, M. S. Gelfand

Research output: Contribution to journalArticlepeer-review

Abstract

We propose a method for comparative analysis of the programs that locate transmembrane segments in proteins. On this basis, we have compiled a sample of beta-barrel protein that allows unequivocal assessment of prediction quality. Upon testing of several Internet servers, B2TMR proves the best, with B2TMPRED, HMM-B2TMR, and PROFtmb following.

Original languageEnglish
Pages (from-to)134-139
Number of pages6
JournalBiophysics (Russian Federation)
Volume53
Issue number2
DOIs
Publication statusPublished - Apr 2008
Externally publishedYes

Keywords

  • Benchmarking of Internet servers
  • Beta-barrel proteins
  • Homologous proteins
  • Testing sample
  • Transmembrane segment prediction

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