Basal ganglia lateralization in different types of reward

Marie Arsalidou, Sagana Vijayarajah, Maksim Sharaev

    Research output: Contribution to journalArticlepeer-review

    14 Citations (Scopus)

    Abstract

    Reward processing is a fundamental human activity. The basal ganglia are recognized for their role in reward processes; however, specific roles of the different nuclei (e.g., nucleus accumbens, caudate, putamen and globus pallidus) remain unclear. Using quantitative meta-analyses we assessed whole-brain and basal ganglia specific contributions to money, erotic, and food reward processing. We analyzed data from 190 fMRI studies which reported stereotaxic coordinates of whole-brain, within-group results from healthy adult participants. Results showed concordance in overlapping and distinct cortical and sub-cortical brain regions as a function of reward type. Common to all reward types was concordance in basal ganglia nuclei, with distinct differences in hemispheric dominance and spatial extent in response to the different reward types. Food reward processing favored the right hemisphere; erotic rewards favored the right lateral globus pallidus and left caudate body. Money rewards engaged the basal ganglia bilaterally including its most anterior part, nucleus accumbens. We conclude by proposing a model of common reward processing in the basal ganglia and separate models for money, erotic, and food rewards.

    Original languageEnglish
    Pages (from-to)2618-2646
    Number of pages29
    JournalBrain Imaging and Behavior
    Volume14
    Issue number6
    Early online date11 Jan 2020
    DOIs
    Publication statusPublished - Dec 2020

    Keywords

    • Basal ganglia
    • fMRI
    • Meta-analyses
    • Rewards
    • Striatum

    Fingerprint

    Dive into the research topics of 'Basal ganglia lateralization in different types of reward'. Together they form a unique fingerprint.

    Cite this