Antioxidant properties of a new water-soluble fullerene c70 derivative

Ekaterina A. Savinova, Elizaveta S. Ershova, Olga A. Kraevaya, Pavel A. Troshin, Svetlana V. Kostyuk

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Citations (Scopus)

Abstract

The search for effective antioxidants is an urgent medical and scientific problem, since oxidative stress causes a number of diseases and accelerates aging of human body. In this paper, we analyzed the ability of a new water-soluble fullerene C70 (F350) derivative to bind reactive oxygen species (ROS) when it was added to human embryonic lung fibroblasts (HELF). We found its nontoxic concentrations for cells, since the fullerene derivatives biosafety assessment is important for the potential application of the nanocomposites in medicine and biology. We also investigated the ability of this fullerene derivative to pass the cell membrane.

Original languageEnglish
Title of host publicationAdvanced Materials in Industrial and Environmental Engineering
EditorsAndrey G. Syrkov, Evgeniy I. Pryakhin, Vyachelsav V. Maksarov, Nikita V. Martyushev
PublisherTrans Tech Publications Ltd
Pages223-229
Number of pages7
ISBN (Print)9783035718027
DOIs
Publication statusPublished - 2020
EventConference on Nanophysics and Nanomaterials, NAN 2019 - St Petersburg, Russian Federation
Duration: 27 Nov 201928 Nov 2019

Publication series

NameKey Engineering Materials
Volume854 KEM
ISSN (Print)1013-9826
ISSN (Electronic)1662-9795

Conference

ConferenceConference on Nanophysics and Nanomaterials, NAN 2019
Country/TerritoryRussian Federation
CitySt Petersburg
Period27/11/1928/11/19

Keywords

  • Antioxidants
  • Human embryonic lung fibroblasts (HELF)
  • Potential application of the nanocomposites in medicine and biology
  • Reactive oxygen species (ROS)
  • Water-soluble fullerene derivative

Fingerprint

Dive into the research topics of 'Antioxidant properties of a new water-soluble fullerene c70 derivative'. Together they form a unique fingerprint.

Cite this