An enzymatic entry to enantiopure β-amino acids

Vadim A. Soloshonok, Vytas K. Svedas, Valery P. Kukhar, Alexander G. Kirilenko, Antonina V. Rybakova, Vladimir A. Solodenko, Nataly A. Fokina, Oleg V. Kogut, Igor YU Galaev, Elena V. Kozlova, Iren P. Shishkina, Sergey V. Galushko

    Research output: Contribution to journalArticlepeer-review

    52 Citations (Scopus)

    Abstract

    A biocatalytic method of preparation of optically pure (>99% e.e.) enantiomers of fluorine-containing and fluorine-free β-amino acids by means of penicillin acylase-catalyzed resolution of their racemic N-phenylacetyl derivatives has been developed.

    Original languageEnglish
    Pages (from-to)339-341
    Number of pages3
    JournalSynlett
    Volume1993
    Issue number5
    DOIs
    Publication statusPublished - May 1993

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