Advanced digital methods for blood flow flux analysis using μpIV approach

Maxim A. Kurochkin, Polina A. Timoshina, Ivan V. Fedosov, Valery V. Tuchin

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Citations (Scopus)

Abstract

A digital optical system focused on work with laboratory animals for intravital capillaroscopy has been developed. It implements the particle image velocimetry (PIV) based approach for measurements of red blood cells velocity in laboratory rat stomach capillaries. We propose a method of involuntary displacement compensation of the capillary network images. Image stabilization algorithm is based on correlation of feature tracking. The efficiency of designed image stabilization algorithm was experimentally demonstrated. The results of capillary blood flow analysis are demonstrated.

Original languageEnglish
Title of host publicationSaratov Fall Meeting 2014
Subtitle of host publicationOptical Technologies in Biophysics and Medicine XVI; Laser Physics and Photonics XVI; and Computational Biophysics
EditorsDmitry E. Postnov, Elina A. Genina, Kirill V. Larin, Vladimir L. Derbov, Valery V. Tuchin
PublisherSPIE
ISBN (Electronic)9781628415643
DOIs
Publication statusPublished - 2014
Externally publishedYes
EventSaratov Fall Meeting 2014: Optical Technologies in Biophysics and Medicine XVI; Laser Physics and Photonics XVI; and Computational Biophysics, SFM 2014 - Saratov, Russian Federation
Duration: 23 Sep 201426 Sep 2014

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9448
ISSN (Print)1605-7422

Conference

ConferenceSaratov Fall Meeting 2014: Optical Technologies in Biophysics and Medicine XVI; Laser Physics and Photonics XVI; and Computational Biophysics, SFM 2014
Country/TerritoryRussian Federation
CitySaratov
Period23/09/1426/09/14

Keywords

  • blood flow flux
  • capillaries blood flow velocity
  • digital image processing
  • Euclidean skeleton
  • image stabilization
  • intravital μPIV
  • native capillaries network
  • optical clearing agent

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